A következő bekezdésnek a végére raktunk egy csillagot, amelyre kattintva egy három sorból, de majdnem 30 ezer karakterből álló gigantikus jegyzet nyílik meg. Nem várjuk, hogy ezt a jegyzetet a szó hétköznapi értelmében bárki elolvassa, mert nem szöveg. Ez csak egy olyan betűsorozat, amely végig négy elemet variál (a, c, g és u). Mind a négy betű egy bizonyos molekulát jelöl, és ha ezek ebben a megadott sorrendben kapcsolódnak egymáshoz, akkor a SARS-CoV-2 vírus RNS-ét, azaz örökítő anyagát alkotják.
Annak, aki hajlandó megnyitni ezt a szekvenciát, középre beletettünk egy törést: 12 karaktert kiemeltünk a 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Ez a 12 molekula a koronavírus egyik, minket nagyon-nagyon rosszul érintő betoldása. Ha ez a 12 molekula nem lenne benne ebben a hosszú polimerben, akkor a vírus felületén lévő tüskeszerű fehérjék nem tudnának ilyen kiválóan kapcsolódni az emberi sejtek falán lévő egyik receptorhoz, és ezért nem tudnának ilyen könnyen bejutni a sejtjeinkbe, azaz nem tudnának ilyen könnyen megfertőzni minket. A 30 ezer tagból álló RNS-ben mindez csak 0,04 százalékos módosítás.
Általános iskolai tanulmányainkból is emlékezhetünk rá, hogy a vírus nem élőlény, csak örökítő anyaga van, vagyis ahhoz, hogy szaporodjon, gazdasejtre van szüksége. Be kell jutnia a sejtjeinkbe, és a SARS-CoV-2 pont ennek a jelentéktelennek tűnő módosításnak köszönheti, hogy ezt sokkal hatékonyabban el tudja érni, mint az elődei.
A 2013-as SARS-járvány koronavírusa (SARS-CoV) hasonló volt, de mégsem ilyen hatékony. Az RNS-ben lévő molekulák sorrendje ugyanis nem más, mint kódok sorozata, amelyek különböző fehérjék legyártására adnak útmutatást. A SARS-CoV-2 újítása pedig pont azért ilyen hatékony, mert az RNS-e a koronavírusokra annyira jellemző, névadó tüskefehérjének egy olyan változatát állítja elő, amelynek alakja jobban illeszkedik az emberi sejt receptorának külsejéhez. Márpedig ha jobban illeszkedik, akkor erősebben, stabilabban tud kötődni hozzá.
A koronavírus-járvány talán minden eddiginél szélesebb körben teszi érthetővé azt, hogy a molekuláris biológia milyen magas fejlettségi szintre jutott, hogy az ember még a molekulák szintjén is milyen alaposan ismeri a természet működését, ám egy 12 molekulás beszúrás ennek ellenére is milyen kiszolgáltatottá tehet minket.
Élet
Hogyan lehet olcsóbb az Afrikából ideszállított eper, mint a magyar?
Az semmi, hogy a görög-spanyol-egyiptomi szamóca olcsóbb, mint a magyar, de lassan a német-holland-belga is az lesz, ha nem fejlesztjük sürgősen az ágazatot.
Külföldi polgármestert is választhatna több magyar település a nagy arányuk alapján
Nem feltétlenül ott él a legtöbb külföldi állampolgár Magyarországon, ahol azt a gazdasági fejlettség alapján várnánk.
Ha így megy tovább, az alapkamat helyett a folyók vízállása határozza meg az inflációt
Eddig a globális felmelegedés árakra gyakorolt hatásait többnyire átmenetinek, esetlegesnek tartották az elemzők, de eljött az ideje a szemléletváltásnak.
Fontos
Egyre több az elektromos autó, egyre több a panasz is Kínában
A kínai vásárlók nagyobb hatótávolságot és jobb tölthetőséget várnak, nő az elektromos autókkal elégedetlenek aránya. Délkelet-Ázsiában ugyanakkor egyre jobban megy a biznisz a kínai gyártók számára.
Olyan lehetőség előtt áll az orosz hadsereg Ukrajnában, mint utoljára két éve
Nem sikerült kihúzniuk az ukránoknak jelentősebb területveszteség nélkül a lőszerutánpótlás és létszámbeli erősítés beérkezéséig, és az is kérdés, nem kerülnek-e még nagyobb bajba.
Amerika részben hátat fordít a fenntarthatóságnak, Európa még kitart
Bár az ESG-célkitűzéseket mindössze néhány évvel ezelőtt állították fel, már annyi feszültséget okoztak, hogy az Egyesült Államokban részben feladták őket.
